In a podcast with Russ Roberts, Manzi says,

Is the number of stars in our galaxy odd or even? Well, there’s a real answer to that question. If you have a bunch of people yelling odd and a bunch of people yelling even, one of those two groups is right. But unless one of them has access to knowledge that I don’t think we have a species right now, we don’t know. And that doesn’t mean it is a theoretically technically unanswerable question, how many stars are in the galaxy, but we don’t have the knowledge right now and we don’t have the capacity of knowledge right now. And that’s the way I feel about that debate.

He is referring to the debate about whether the stimulus created jobs. As you know, I think his book, Uncontrolled is excellent. The podcast is also recommended.